19th Funniest Comic Book - X-Factor

Peter David had quite the task cut out for him - take a bunch of fairly random X-Characters, put them together on a team, and then try to sell a mutant HUMOR title?

And yet, David managed to pull it off, creating a hilarious superhero title with such minor characters as Madrox and Guido, turning these minor characters into characters so popular that, years later, David was able to revisit the title, bringing the characters back together for the current (much more serious) title, X-Factor.